ICCB-19 HCl（750621-52-4 free base） ( —— )

产品货号. M23816 CAS No. 1803605-68-6

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

ICCB-19 HCl（750621-52-4 free base）
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).
产品描述

ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain).?It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
同义词

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通路

Others
靶点

Other Targets
受体

TRADD
研究领域

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适应症

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1.Xu D , Zhao H , Jin M , et al. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis[J]. Nature, 2020, 587(7832):1-6.

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